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GLP-1 Weight Loss Clinics in Sioux Falls, South Dakota

Sioux Falls has 40 GLP-1 clinics offering semaglutide and tirzepatide, with common service models including Weight Loss, Wellness, Weight Management. The average rating is 4.8 out of 5 across 5772 reviews. 8% of clinics indicate they accept insurance, and 13% mention telehealth availability.

Sioux Falls patients can use this page to compare local listings, then branch into the wider South Dakota market for nearby options if the best fit is outside city limits. You can also browse every GLP-1 clinic in South Dakota, compare semaglutide vs tirzepatide options, and read our guide on how to compare GLP-1 clinics before choosing a practice.

40
Clinics in Sioux Falls
4.8★
Average rating
8%
Accept insurance
13%
Offer telehealth

Clinic Map — Sioux Falls, South Dakota

40 GLP-1 Clinics in Sioux Falls

Click column headers to sort. Click a clinic name for full details.

ClinicRating
Encompass Wellness & AestheticsSioux Falls, SD5.0(311)
Encompass Wellness & AestheticsSioux Falls, SD5.0(14)
Era HealthSioux Falls, SD5.0(37)
Gameday Men's Health Sioux Falls TRT, Peptide, and ED ClinicSioux Falls, SD5.0(111)
Hormones Gone WildSioux Falls, SD5.0(8)
ivclub - iv&co.Sioux Falls, SD5.0(65)
Jenny Craig Weight Loss CenterSioux Falls, SD5.0(1)
Kimberly Dewing, PA-CSioux Falls, SD5.0(11)
Liv Med Spa | Sioux Falls, SDSioux Falls, SD5.0(116)
LIVE Hydration Spa Sioux FallsSioux Falls, SD5.0(0)
LivWell - Sioux FallsSioux Falls, SD5.0(0)
Long Island weight loss doctor Dr Howard GoodmanSioux Falls, SD5.0(421)
Novo AestheticsSioux Falls, SD5.0(0)
Radiant Health and Hormone TherapySioux Falls, SD5.0(9)
Refined AestheticsSioux Falls, SD5.0(708)
Sanford Weight Management CenterSioux Falls, SD5.0(0)
The Confidence CollectiveSioux Falls, SD5.0(121)
The Retreat at Cedar Creek - Sioux Falls Weight Loss, Red Light Body Contouring & Wellness CenterSioux Falls, SD5.0(11)
Vibrance Medical, PLLCSioux Falls, SD5.0(16)
Vital Flow InfusionsSioux Falls, SD5.0(252)
WW Studio Sioux FallsSioux Falls, SD5.0(1)
Dawn A. Flickema, MDSioux Falls, SD4.9(0)
LaVie Ideal Protein Virtual ClinicSioux Falls, SD4.9(12)
Niagara Wheatfield Medical Weight Loss ServicesSioux Falls, SD4.9(27)
Prime IV Hydration & Wellness - Sioux FallsSioux Falls, SD4.9(0)
Profile Plan - Personalized Weight Loss Plans (Virtual Location)Sioux Falls, SD4.9(162)
Sioux Falls Secret for Weight LossSioux Falls, SD4.9(34)
SummaUpSioux Falls, SD4.9(76)
Trillion Health and Hormone ClinicSioux Falls, SD4.9(129)
Accelerate Wellness - Longevity Medicine ClinicSioux Falls, SD4.8(0)
Long Island Weight Loss InstituteSioux Falls, SD4.8(190)
Medical Weight Loss SolutionsSioux Falls, SD4.8(53)
Limitless Male Medical ClinicSioux Falls, SD4.6(102)
New York Stock ExchangeSioux Falls, SD4.3(2762)
Functional Health ClinicSioux Falls, SD4.0(4)
Avera Comprehensive Weight Management — 41st & HolbrookSioux Falls, SD2.6(8)
Avera Center-Medical NutritionSioux Falls, SDNo reviews
Healthy Systems USASioux Falls, SDNo reviews
Ideal Weight Loss ProgramSioux Falls, SDNo reviews
Simply Ideal Weight LossSioux Falls, SDNo reviews

FAQ: GLP-1 Clinics in Sioux Falls

How many GLP-1 clinics are in Sioux Falls?

40 clinics in Sioux Falls, South Dakota are listed on GLP-1 Near as of March 2026.

Do Sioux Falls GLP-1 clinics accept insurance?

8% of listed GLP-1 clinics in Sioux Falls indicate that they accept insurance. Coverage still varies by plan and provider.

Are there telehealth GLP-1 options in Sioux Falls?

Yes. 13% of listed clinics in Sioux Falls mention telehealth or virtual GLP-1 care options.

What is the average rating of GLP-1 clinics in Sioux Falls?

The average listed rating is 4.8 out of 5 from 5772 total reviews.

Keep Exploring Sioux Falls GLP-1 Options

Start with the full South Dakota directory, then compare medication paths on our semaglutide vs tirzepatide page.

Helpful next reads: how to compare GLP-1 clinics · what solid telehealth GLP-1 care should include